Disproportionately enlarged subarachnoid space hydrocephalus presence in patients with idiopathic normal pressure hydrocephalus

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Idiopathic Normal Pressure Hydrocephalus

Idiopathic normal pressure hydrocephalus (iNPH) is a potentially reversible neurodegenerative disease commonly characterized by a triad of dementia, gait, and urinary disturbance. Advancements in diagnosis and treatment have aided in properly identifying and improving symptoms in patients. However, a large proportion of iNPH patients remain either undiagnosed or misdiagnosed. Using PubMed searc...

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Neuropsychiatric Symptoms in Patients with Idiopathic Normal Pressure Hydrocephalus

OBJECTIVE To clarify the characteristics of neuropsychiatric symptoms in patients with idiopathic normal pressure hydrocephalus (iNPH). METHODS Neuropsychiatric symptoms of 64 iNPH patients with mild triad symptoms from three kinds of hospitals were evaluated with the Neuropsychiatric Inventory (NPI) and compared with 126 patients with Alzheimer's disease (AD). RESULTS The most frequently o...

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Changes in the subarachnoid space precede ventriculomegaly in idiopathic normal pressure hydrocephalus (iNPH).

We report on an 80-year-old woman who had shunt-responsive idiopathic normal pressure hydrocephalus (iNPH). Her brain MRI showed an initial change in the subarachnoid space (a disproportional narrowing of the subarachnoid space at the cerebral high convexities) at the age of 70 years, followed by enlargement of the ventricles (Evans index: 0.31) at the age of 78. The observation suggests that c...

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Idiopathic normal pressure hydrocephalus in neurological practice

Background: We have previously seen that idiopathic normal pressure hydrocephalus (iNPH) patients havingelevated intracranial pressure (ICP) pulse amplitude consistently respond to shunt surgery. In this study weexplored how the cerebrospinal fluid pressure (CSFP) pulse amplitude determined during lumbar infusion testing,correlates with ICP pulse amplitude determined during over-nig...

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Glymphatic MRI in idiopathic normal pressure hydrocephalus

The glymphatic system has in previous studies been shown as fundamental to clearance of waste metabolites from the brain interstitial space, and is proposed to be instrumental in normal ageing and brain pathology such as Alzheimer's disease and brain trauma. Assessment of glymphatic function using magnetic resonance imaging with intrathecal contrast agent as a cerebrospinal fluid tracer has so ...

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ژورنال

عنوان ژورنال: Fluids and Barriers of the CNS

سال: 2015

ISSN: 2045-8118

DOI: 10.1186/2045-8118-12-s1-p43